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| Blood Donation |
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No other department in a pathological lab carries
the same degree of responsibility as that of the
blood bank, for in no other department is an error
so likely to result in the
death of a patient. So, double-checking of the
blood is always a must. The Drugs & Cosmetics
Act has stipulated stringent standards for blood
banks and because of this licensed blood banks
have been few in number although, of late, new
blood banks have been licensed in view of the
extensive development of medical services.
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| What is Blood? |
| Over the centuries blood has been regarded as
the essence of life itself. From the beginning of
time until the early 20th century blood loss was
a common cause of death. Blood is made of straw-colored
fluid called Plasma in which are suspended many
tiny living cells. These are mostly Red Blood Cells,
with some White Cells and smaller cells called Platelets.
Altogether the cellular components make up 45% of
the blood volume. The rest is fluid.
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| Percentage of blood is in the body? |
| Approximately 8% of the body weight are blood.
Thus a person weighing 50 Kg would have about 4000-ml
blood. The average adult has about 5000 ml of blood.
Blood volume changes slightly in the same person
from time to time, varying with hot weather, muscular
exercise, high altitudes and pregnancy.
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| What are blood groups? |
| Complex chemical substances found on the surfaces
of red blood cells are different for each blood
group. The two most important blood group systems
in transfusion work are the ABO and Rh systems.
Within the ABO system people can be one of four
types O, A, B or AB, whilst in the Rh system
they can be either Rh positive or Rh negative.
Each system is inherited independently of the
other. Thus, there are eight main blood groups.
They are, from the most common to the rarest:
O positive
A positive
O negative
B positive
A negative
B negative
AB positive
AB negative
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| Who can donate Blood ? |
Any healthy adult, both male and female, can donate
blood. Men once in every Three months and women
every Four months. Good health of the donor must
be fully ensured. The universally accepted criteria
for donor selection are:
- Age between 18 and 55 years
- Haemoglobin not less than 12.5 g/dL
- Pulse between 50 and 100/minute with
no irregularities
- Blood Pressure Systolic 90 180
mm Hg and Diastolic 50 100 mm Hg
- Temperature Normal (oral temperature
not exceeding 37.5 degree C)
- Body weight not less than 46 Kg
- Health conditions:
- Past one year not been treated for Rabies,
had Jaundice, tested positive for Hepatitis
B virus or received Hepatitis B immune globulin.
- Past six months a tattoo, ear or skin
piercing or acupuncture, received blood or blood
products, serious illness or major surgery,
contact with a person with hepatitis or yellow
jaundice.
- Past three months donated blood or
been treated for Malaria.
- Past one month had any immunizations.
- Past 48 hours taken any antibiotics
or any other medications (Allopathic or Ayurveda
or Sidha or Homeo)
- Past 24 hours taken alcoholic beverages
- Past 7 hours had dental work or taken
Aspirin
- Present suffering from cough, Flue
or sore throat, cold, pregnancy or breast feeding
- Free from Diabetes, not suffering from chest
pain, heart disease or high BP, cancer, blood
clotting problem or blood disease, unexplained
fever, weight loss, fatigue, night sweats, enlarged
lymph nodes in armpits, neck or groin, white
patches in the mouth etc
- Lived in the Islands of West Africa, Haiti
or Africa since 1970
- Ever had TB, bronchial asthma or allergic
disorder, liver disease, kidney disease, fits
or fainting, blue or purple spots on the skin
or mucous membranes, received human pituitary
growth hormones etc
To find out the eligibility of the blood donors
and to rule out any contra indication for blood
donation all the donors will be elaborately interrogated
for the history and the incidence of the specific
ailments by a planned questionnaire. Only after
satisfactorily fulfilling the laid down basic
criteria, the blood donors will be selected.
After blood collection, as a routine and mandatory
procedure, the donors blood specimens will
be screened for Malaria, Syphilis, Hepatitis B,
Hepatitis C, HIV 1 & 2 antibodies etc.
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| Who should not donate blood ? |
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The following categories of people should avoid
giving blood:
- Pregnant or lactating women, or those who
have recently had an abortion.
- Persons who are on steroids, hormonal supplements
or certain specified medication.
- Persons with multiple sexual partners or
those who are addicted to drugs.
- Persons who have had an attack of infection
like jaundice, rubella, typhoid or malaria.
- Persons who have undergone surgery in the
previous six months.
- Persons who have consumed alcohol in the
24 hours prior to donation.
- Women should avoid donation during their
menstruating period.
- Those who have undergone various vaccinations
should avoid donation for the corresponding
period specified below:
|
Type
of Vaccine
|
The
period in which donation should be avoided |
Hepatitis
B
Live vaccines
Killed vaccines
Rabies |
6 months
2 weeks
48 Hours
1 year
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9. Persons with any systemic disease like heart
disease, kidney disease, liver problems, blood
disorders or asthma should NOT donate blood.
10. Persons suffering from infections transmitted
through transfusions like HIV, Hepatitis, Syphilis
etc should Not donate blood.
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| Blood Components and
their Uses |
| What is whole Blood ? |
| Whole blood is a standard bag of blood mixed with
a liquid chemical, which prevents clotting. Whole
blood is used mainly when there is massive bleeding
and is required infrequently in transfusion therapy.
Whole blood can be separated into several components
after spinning in a centrifuge
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| What are blood components ? |
- Many cellular and protein components of blood
can be separated from each other. Each blood
component can then be used to replace a specific
blood deficiency. Components are prepared from
fresh blood. The whole blood pack is spun in
a refrigerated centrifuge.
- RED CELL CONCENTRATES are the most widely
used blood components. Most patients requiring
transfusions are in need of the oxygen-carrying
capacity of the red cells. Of these a few require
whole blood, but most are best treated by using
only red cells for treatment of anaemia and
chronic blood diseases.
- PLASMA is separated by spinning in a refrigerated
centrifuge. It is used for treatment of some
coagulation disorders.
- PLATELET CONCENTRATES are used to control
bleeding due to platelet deficiency. These may
be caused by a disease e.g. Leukaemia or may
follow severe haemorrhage. Platelet concentrates
can be stored for up to 5 days.
- CRYOPRECIPITATE is widely used for treatment
of haemophilia A, the most common inherited
bleeding disease.
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